Research Interests and Activities
My research program focuses on the exposome and on the development of methods to measure it, which we call exposomics. We combine elements of environmental analytical chemistry and informatics to understand the wide range of environmental contaminants in the environment and in our bodies. Through toxicology and epidemiological studies we also aim to understand the adverse impacts these exposures have on health. In particular I’m interested in early-life exposures to organic contaminants that may alter the developmental of humans or wildlife.
My research group has developed the Ultratrace Non-Target Laboratory (UNTARGET Lab) at Science for Life Laboratory (SciLifeLab) which houses ultrahigh resolution mass spectrometers for discovery of important new chemical contaminants in air, water, and human biofluids. The surrounding research environment at SciLifeLab specializes in genomics, epigenomics, proteomics, functional biology, bioimaging, and biostatistics, creating great possibilities to investigate our questions using best-available biomolecular technologies and methods.
I completed my doctoral degree in toxicology at University of Guelph in 2002, and then trained in environmental chemistry at University of Toronto as a postdoctoral fellow in 2003. I was awarded an NSERC fellowship to continue my postdoctoral training in pharmaceutical sciences at University of Toronto in 2004. I then worked as a Professor at University of Alberta from 2004-2016, and moved to Stockholm University and SciLifeLab in 2017. My research group’s publications are accessible on Google Scholar and have been ‘Highly Cited’ (Thomson Reuters, 2014). I’m an elected member of the Royal Society of Canada’s College of New Scholars, Artists and Scientists. Since 2020 I have served as Associate Editor for Environmental Science & Technology Letters.
Current Postdoctoral Fellows:
Current PhD Students:
Dr. Lisa D’Agostino
Dr. Ioannis Sadiktsis
Latest scientific papers
Nontarget mass spectrometry and in silico molecular characterization of air pollution from the Indian subcontinent
Revisiting old lessons from classic literature on persistent global pollutants This article belongs to Ambio’s 50th Anniversary Collection. Theme: Environmental contaminants
Interaction of prenatal bisphenols, maternal nutrients, and toxic metal exposures on neurodevelopment of 2-year-olds in the APrON cohort
Nontarget analysis reveals gut microbiome-dependent differences in the fecal PCB metabolite profiles of germ-free and conventional mice
Effects of prenatal exposure and co-exposure to metallic or metalloid elements on early infant neurodevelopmental outcomes in areas with small-scale gold mining activities in Northern Tanzania