The ITN (Innovative Training Network) PERFORCE3 (PER and polyfluorinated alkyl substances (PFASs) towards the Future Of Research and its Communication in Europe 3) is a Europe-wide multi-partner doctoral research training programme in the field of PFASs contaminants coordinated by Stockholm University and funded by the European Union’s Horizon 2020 research and innovation programme under its Marie Skłodowska-Curie Actions. PFASs comprise more than 4’700 substances and are of high global concern due to poorly defined risks to the environment and human health. PERFORCE3 will greatly improve the understanding of these globally pervasive contaminants, find solutions for PFAS contamination problems and improve environmental and human health risk assessment frameworks and policies.

The ITN PERFORCE3 brings together world leaders in a range of disciplines (physical, synthetic, environmental and analytical chemistry, pharmacokinetics, epidemiology, toxicology, remediation science and chemical policy) with state-of-the-art technologies, providing high quality doctoral training and research environments to 15 Early Stage Researchers (ESRs). The training includes independent research work in individual yet interlinked research projects and a well-structured training programme including technical and professional transferable skills courses, network meetings and workshops as well as lab visits and secondments. Participation in PERFORCE3 will equip young scientists with research and transferable skills and competences, while fostering their creativity, innovation and entrepreneurship and boosting their career perspectives through international, interdisciplinary and inter-sectoral mobility opportunities.

ESR Project 1
Advanced mass spectrometric techniques combined with chemometrics methods to identify emerging and novel PFASs in humans and in human exposure media
Host organization: UFZ – Helmholtz Centre for Environmental Research (Germany)
Main supervisor and contact: Thorsten Reemtsma

ESR Project 2
Combustion ion chromatography and advanced oxidation as a tool for rapid screening of PFAA-precursors in consumer products and environmental media at contaminated sites
Host organization: Stockholm University (Sweden)
Main supervisor and contact: Jonathan Benskin

ESR Project 3
Release of known and unknown PFASs to the atmosphere and resulting human exposure
Host organization: Stockholm University (Sweden)
Main supervisor and contact: Ian Cousins

ESR Project 4
Fate and properties of alternative and unknown PFASs in the drinking water cycle and its significance for human exposure
Host Organization: University of Amsterdam (The Netherlands)
Main supervisor and contact: Annemarie van Wezel

ESR Project 5
Evaluating the role of the dermal pathway in driving human exposure to PFAS.
Host Organization: University of Birmingham (UK)
Main supervisor and contact: Stuart Harrad

ESR Project 6
In vitro studies to characterize the impact of legacy and replacement PFAS and of human-relevant PFAS mixtures on cholesterol homeostasis in human liver cells
Host organization: German Federal Institute for Risk Assessment (Germany)
Main supervisor and contact: Albert Braeuning

ESR Project 7
Targeted and non-target cell-based metabolomics and lipidomics to identify molecular mechanisms and pathways involved in toxicity of PFASs
Host organization: VU Amsterdam (The Netherlands)
Main supervisor and contact: Pim Leonards

ESR Project 8
PFAS and total organofluorine exposure over time and dietary predictors in two Norwegian cohorts.
Host organization: Norwegian Institute for Air Research NILU (Norway)
Main supervisor and contact: Dorte Herzke

ESR Project 9
The effects of legacy and replacement PFAS on gene expression and metabolome
Host organization: UiT -The Arctic University of Norway (Norway)
Main supervisor and contact: Torkjel M Sandanger

ESR Project 10
Dose-response assessment of PFAS mixtures in relation to biomarkers of effects relevant for cardiovascular disease in humans
Host organization: Karolinska Institutet (Sweden)
Main supervisor and contact: Mattias Öberg

ESR Project 11
Innovative treatment techniques for PFASs in stormwater, groundwater, wastewater and landfill leachate
Host organization: Swedish University of Agricultural Science (Sweden)
Main supervisor and contact: Karin Wiberg

ESR Project 12
Developing innovative treatment techniques for materials and groundwater contaminated with PFASs
Host organization: Swedish University of Agricultural Science (Sweden)
Main supervisor and contact: Lutz Ahrens

ESR Project 13
Advancing transport models and in situ remediation techniques for PFAS contamination in unsaturated soil
Host organization: Norwegian Geotechnical Institute – NGI (Norway)
Main supervisor and contact: Hans Peter H. Arp

ESR Project 14
Synthesis and biodegradation of novel PFASs utilizing advanced mass spectrometric techniques combined with chemometric methods
Host organization: Hochschule Fresenius -University of Applied Sciences (Germany)
Main supervisor and contact: Thomas Knepper

ESR Project 15
Comprehensive assessment of alternatives to long-chain PFASs and policy recommendations for the assessment and management of PFASs
Host organization: ETH Zuerich (Switzerland)
Main supervisor and contact: Martin Scheringer

Further information and inquiries

For further information concerning a specific position, please contact the respective main supervisor as listed above.

For general inquiries regarding PERFORCE3, please contact: perforce3@aces.su.se. For further information on Marie Skłodowska-Curie Actions, please visit: https://ec.europa.eu/research/mariecurieactions/

Stockholm University (SE)

Consortium members:
Stockholm University (SE), Karolinksa Insitutet (SE), Norwegian Institute for Air Research NILU (NO), UiT -The Arctic University of Norway (NO), VU Amsterdam (NL), University of Amsterdam (NL), University of Birmingham (UK), ETH Zuerich (CH), Helmholtz Centre for Environmental Research – UFZ (DE), Hochschule Fresenius -University of Applied Sciences (DE), German Federal Institute for Risk Assessment (DE), Norwegian Geotechnical Institute– NGI (NO), Swedish University of Agricultural Sciences (SE),

The Organisation for Economic Co-operation and Development (FR), Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences (CN), The Chemours Company (US), KWR Watercycle Research Institute (NL), Federal Environment Agency (DE), Chiron (NO), Swedish Chemicals Agency (SE), Merck (DE), Swedish Water and Wastewater Association (SE), Norwegian University of Science and Technology (NO), GE Healthcare Biosciences AB (SE)

Contact information

Visiting addresses:

Geovetenskapens Hus,
Svante Arrhenius väg 8, Stockholm

Arrheniuslaboratoriet, Svante Arrhenius väg 16, Stockholm (Unit for Toxicological Chemistry)

Mailing address:
Department of Environmental Science
Stockholm University
106 91 Stockholm

Press enquiries should be directed to:

Stella Papadopoulou
Science Communicator
Phone +46 (0)8 674 70 11

Project Info

Project start: 2020

This Project is part of Research topic