What contributes to human body burdens of phthalate esters? An experimental approach.
Phthalate esters (PEs) and alternative plasticizers are widely used as additives to obtain suitable flexibility and durability of polymeric products. Since they are not covalently bonded to the material they can easily get released into the air or leach from the products, contaminating the environment. The overall goal of the project is to elucidate the routes of human exposure to phthalate esters and alternative plasticizers. Analytical methods have been developed to quantify concentrations in air, dust, hand-wipes and dietary products, in order to investigate the contribution of different external human exposure pathways such as inhalation, dietary and dust ingestion and dermal absorption in a Norwegian cohort of 61 adults. Analysis of phthalate and plasticizer metabolites in human urine, fingernails and saliva will determine the internal dose. The relationship between external and internal exposure will be further investigated using modelling techniques.
Latest scientific papers
Case Study on Screening Emerging Pollutants in Urine and Nails
Phthalates, non-phthalate plasticizers and bisphenols in Swedish preschool dust in relation to children’s exposure
Evaluation of exposure to phthalate esters and DINCH in urine and nails from a Norwegian study population
Comprehensive Study of Human External Exposure to Organophosphate Flame Retardants via Air, Dust, and Hand Wipes: The Importance of Sampling and Assessment Strategy.
Human exposure, hazard and risk of alternative plasticizers to phthalate esters