I conduct research within the field of regulatory toxicology. My principal aim is to contribute to national and international efforts to improve regulatory risk assessment of endocrine disrupting compounds (EDCs).
There is a global concern that EDCs may be contributing to observed increases in endocrine-related disease in the human population, as well as effects in the environment. However, risk assessment of EDCs has proven complicated and is often hampered by large scientific uncertainties. One primary reason is the complex toxicity exhibited by hormonally active substances, which challenges the methods, assumptions and principles traditionally applied in toxicity testing and risk assessment. My work focuses on how these uncertainties can be reduced or handled. I am especially interested in how methods for evaluating reliability and relevance of data for risk assessment, as well as for conducting weight of evidence evaluations, can be developed and improved. Literature studies that scrutinize risk assessments and scientific literature, as well as relevant legislation and other policy documents, provide the basis for my research.
Latest scientific papers
Weight of Evidence evaluation and Systematic Review in EU chemical risk assessment: Foundation is laid but guidance is needed
Combining web‐based tools for transparent evaluation of data for risk assessment: developmental effects of bisphenol A on the mammary gland as a case study
A proposed framework for the systematic review and integrated assessment (SYRINA) of endocrine disrupting chemicals
Science in Risk Assessment and Policy (SciRAP): an online resource for evaluating and reporting in vivo (eco) toxicity studies